Key result
Exercise, cold exposure, and hibernation fail to extinguish rodent biological rhythms, demonstrating their remarkable fixity.
Population
Mammals (rodents)
Design
Preclinical
Authors
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Rodent rhythms resist common disruptors; leaves open translation to human cardiovascular chronobiology and should not yet change practice.
The study demonstrates the fixity of biological rhythms in rodents despite cold exposure, exercise, and hibernation.
G. Edgar Folk (1957) studied Biological rhythms. Exercise, cold exposure, and natural hypothermia (hibernation) was evaluated on Extinguishment or separation of biological rhythms. Exercise, cold exposure, and hibernation failed to extinguish most rodent biological rhythms, demonstrating their remarkable fixity and the close linkage of physiological rhythms.
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