The development of a technique of intravenous catheterization and its application to the sampling of renal venous blood (1) have made possible the study of the metabolic activity of the kidney in the unanesthetized human subject.We have used this method of investigation in conjunction with the usual clearance procedures in an attempt to determine the oxygen consumption of the normal kidney and its variation in disease.
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Cargill et al. (1949) studied this question.
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