Down-Regulation of theEscherichia coliK-12nrfPromoter by Binding of the NsrR Nitric Oxide-Sensing Transcription Repressor to an Upstream Site

This is the authors' abstract. We don't add key points for this paper.

FNR-dependent activation of the Escherichia coli K-12 nrf promoter is downregulated by the nitric oxide-sensitive NsrR protein together with the nucleoid-associated protein IHF, which bind to overlapping targets adjacent to the DNA site for FNR. The NsrR target is inactivated by mutation at the Salmonella enterica serovar Typhimurium nrf promoter.