Total Synthesis and Determination of the Absolute Configuration of (−)‐Dolabriferol

This is the authors' abstract. We don't add key points for this paper.

A reaction cascade combining sulfur dioxide with a 1-oxy-1,3-diene and (E)-silyl enol ether formed the basis of a short total synthesis of (−)-dolabriferol (see scheme; TMS=trimethylsilyl). The absolute configuration of this natural product, which was first extracted from a gastropod mollusc in 1996, was established unequivocally.