Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
October 8, 2015Journal of Thoracic Imaging

Multidetector Computed Tomography Findings in Pulmonary Hamartomas

View Full Paper
Ask AI
Bookmark
Share

Key result

A <-33 HU CT threshold detects pulmonary hamartoma fat with ~95% accuracy, outperforming -40 HU.

  • n=55

Why the study?

Does a revised density threshold (<-33 HU) on multidetector computed tomography improve the accuracy of fat detection in pulmonary hamartomas compared to a -40 HU threshold?

Population

55 patients who had received a histologically confirmed diagnosis of pulmonary hamartomas and had undergone…

Comparison

64-slice thoracic multidetector computed… vs Histologic analysis and MDCT using a standard…

Design

Cohort

Authors

BHBruno HochheggerUniversity of FloridaCNCarlos Schüler NinGAGiordano Rafael Tronco AlvesHumanitas University

Discussion

Loading...

Member takes

Implication

May support <-33 HU threshold for fat detection in pulmonary hamartomas on CT; leaves open prospective validation before practice change.

Study Design

Type

Observational (n=55)

Structured PICO

Does a revised density threshold (<-33 HU) on multidetector computed tomography improve the accuracy of fat detection in pulmonary hamartomas compared to a -40 HU threshold?

P
Population
55 patients with histologically confirmed pulmonary hamartomas who underwent 64-slice thoracic MDCT.
E
Exposure
64-slice thoracic multidetector computed tomography (MDCT) using a density threshold of <-33 HU for fat detection
C
Comparator
Histologic analysis (gold standard) and MDCT using a standard density threshold of -40 HU
O
Outcome
Accuracy, sensitivity, and specificity of fat detectionsurrogate

Main Result

Absolute Event Rate: 95.3% vs 83.7%

Adopting a density threshold of <-33 HU on multidetector computed tomography significantly improves the accuracy and specificity of detecting fat in pulmonary hamartomas.

Cite This Study

Hochhegger et al. (2015) conducted an observational in Pulmonary hamartomas (n=55). CT density threshold of <-33 HU for fat detection vs. CT density threshold of -40 HU was evaluated on Accuracy of fat detection. A CT density threshold of <-33 HU for fat detection in pulmonary hamartomas yielded 95.3% accuracy, 100% sensitivity, and 96.3% specificity, improving upon the -40 HU threshold.

synapsesocial.com/papers/6aa52da13f91f0dc5278e3e6https://doi.org/10.1097/rti.0000000000000180
View Full Paper
Ask AI
Bookmark
Share

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Multi–Detector Row Spiral CT Pulmonary Angiography: Comparison with Single–Detector Row Spiral CT2001 · 157 citations
  2. 2Pulmonary hamartoma: CT findings.1986 · 286 citations
  3. 3Videothoracoscopic identification of chondromatous hamartoma of the lung.2013 · 5 citations
  4. 4Sources of Error in Lung Densitometry with CT1999 · 66 citations
  5. 5Performance evaluation of a multi-slice CT system1999 · 388 citations