Key result
Adding pericardial fluid in dogs nonlinearly decreases body-surface potentials, matching the eccentric spheres model.
Authors
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May artifactually alter ECG voltages in pericardial effusion; leaves open clinical translation of eccentric spheres model.
Kramer et al. (1984) studied this question. Addition of fluids of various conductivity to the pericardial sac vs. Predictions based on a mathematical eccentric spheres model was evaluated on Changes in body-surface potentials. Addition of fluids of varying conductivity to the pericardial sac in dogs caused a nonlinear decrease in anterior chest body-surface potentials, accurately predicted by the eccentric spheres model.
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