Key result
Carotid plaques linked to ~56% greater ASCVD risk in asymptomatic high-risk patients.
Why the study?
Does carotid artery evaluation predict first ASCVD events in asymptomatic high-risk patients without known ASCVD?
Cohort (n=873)
No
Does carotid artery evaluation predict first ASCVD events in asymptomatic high-risk patients without known ASCVD?
Hazard Ratio: 1.556 (95% CI 1.009–2.4)
p-value: p=0.045
The presence of carotid plaques provides additional predictive value for primary prevention of ASCVD in asymptomatic high-risk patients, particularly in middle-aged individuals.
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May refine ASCVD risk stratification in asymptomatic high-risk patients; leaves open prospective validation before practice change.
Kim et al. (2015) conducted a cohort in Asymptomatic high-risk patients without ASCVD (n=873). Carotid plaques vs. Absence of carotid plaques was evaluated on ASCVD events (HR 1.556, 95% CI 1.009-2.400, p=0.045). The presence of carotid plaques was significantly associated with an increased risk of ASCVD events in asymptomatic high-risk patients (HR 1.556; 95% CI 1.009-2.400; P=0.045).
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