An Efficient and General Procedure for the Cross-Coupling of Trimethylsilylacetylene and Vinylic, Aromatic or Heteroaromatic Bromides

Coupling reactions of trimethylsilylacetylene and vinylic, aromatic or heteroaromatic bromides can be carried out in very short time and with excellent yield using piperidine as a solvent and very small amounts of tetrakis(triphenylphosphine)palladium and copper(I)iodide (0.1 to 0.3 g on 100 mmol scale) as catalysts.