Key result
Heavy alcohol intake is linked to acute myopathy with elevated CPK that improves after cessation.
Why the study?
Does cessation of alcohol consumption improve symptoms and CPK levels in patients with alcoholic muscle disease?
Case Report (n=4)
Does cessation of alcohol consumption improve symptoms and CPK levels in patients with alcoholic muscle disease?
Heavy alcohol intake can cause an acute myopathy that mimics deep venous thrombosis and improves with alcohol cessation.
Answers are grounded in this paper and cite their sources.
Alcohol cessation may aid acute myopathy with elevated CPK; case reports leave causality and practice change open.
The effect of ethyl alcohol on striated muscle: some clinical and pathological observations. J. C. Walsh and A. B. Conomy, Aust. N.Z. J. Med. 1977, 7, pp. 485–490. Electrophysiological and pathological studies have been performed on three patients with recurrent focal swelling of the calf muscles simulating deep venous thrombosis, and in a patient with both cardiomyopathy and skeletal muscle disease. In all patients there were elevated CPK levels, histological evidence of an acute myopathy, heavy alcohol intake prior to the development of symptoms, and improvement in hospital with the cessation of alcohol consumption. These patients illustrate a form of alcoholic muscle disease which may be more common than generally realised.
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Walsh et al. (1977) conducted a case report in Alcoholic muscle disease (n=4). Heavy alcohol intake vs. Cessation of alcohol consumption was evaluated on Clinical and pathological features of myopathy and response to alcohol cessation. Heavy alcohol intake was associated with an acute myopathy characterized by elevated CPK levels and focal muscle swelling, which improved upon cessation of alcohol consumption.
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