Generation of 2-Substituted-2-metallo-1,3-dithianes and Their Coupling with 1,2-Disubstituted Epoxides at Room Temperature

All articles of this category 2-Substituted 1,3-dithianes were subjected to lithiation by n -BuLi at room temperature and the resulting anions reacted with 1,2-disubstituted epoxides at room temperature, giving the coupling products in satisfactory yield. In addition, a mixed organometallic reagent, n -BuLi/Bu 2 Mg, was found to be an effective metallation reagent for 2-substituted-1,3-dithianes. dithiane coupling - 2-substituted-1,3-dithianes - 1,2-disubstituted epoxides - n -BuLi/Bu 2 Mg complex