Key result
Left bundle branch area pacing successfully achieved cardiac resynchronization in a patient with heart failure, complete left bundle branch block, and atrial tachycardia, increasing LVEF from 34% to 73% at 1 year.
Why the study?
Optimal treatment strategy warrants discussion for patients with heart failure combined with complete left bundle branch block who also present with atrial tachycardia.
Does left bundle branch area pacing improve systolic function in a patient with heart failure, complete left bundle branch block, and atrial tachycardia?
Case Report (n=1)
Does left bundle branch area pacing improve systolic function in a patient with heart failure, complete left bundle branch block, and atrial tachycardia?
Left bundle branch area pacing can be an effective alternative for cardiac resynchronization therapy in patients with heart failure, complete LBBB, and atrial tachycardia when traditional biventricular pacing fails.
Answers are grounded in this paper and cite their sources.
Should not yet change CRT practice in HF with LBBB and atrial tachycardia; leaves open efficacy of LBBAP beyond single cases.
BACKGROUND: For patients with heart failure combined with complete left bundle branch block, cardiac resynchronization therapy is an important therapeutic method. If these patients also have atrial tachycardia, how to choose a treatment strategy deserves discussion. CASE PRESENTATION: A Chinese woman in her early 70s was admitted due to recurrent episodes of chest distress and asthma for 1 year. Physical and laboratory examinations showed filling of the jugular vein, lung rales, left enlargement of the heart boundary, edema of the lower limbs and elevation of N-terminal pro b-type natriuretic peptide. An electrocardiogram showed atrial tachycardia and a left bundle branch block. An echocardiography revealed enlargement of the left ventricle and left ventricular systolic dysfunction. After obtaining informed consent, the treatment strategy decided upon by the team was to use biventricular cardiac resynchronization therapy treatment and to not intervene for the atrial tachycardia, with left bundle branch area pacing as a backup. Due to twisted and narrow coronary vein branches, traditional biventricular pacing failed, and then, left bundle branch area pacing was attempted successfully. A follow-up echocardiography at 1 year showed improved systolic function. The outcomes for this patient are favorable, but the choice of interventional strategy is worthy of discussion in this case. CONCLUSION: For patients with heart failure combined with left bundle branch block and atrial tachycardia, left bundle branch area pacing can replace traditional biventricular pacing for cardiac resynchronization therapy treatment, and the therapeutic effect is significant. However, multiple factors need to be considered when formulating strategies, including whether there is bundle branch block under sinus rhythm, the success and recurrence rate of atrial tachycardia ablation, the response of cardiac resynchronization therapy, the costs of different strategies, and instrument implantation issues.
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Wang et al. (2024) conducted a case report in Heart failure complicated with complete left bundle branch block and atrial tachycardia (n=1). Left bundle branch area pacing was evaluated on Left ventricular ejection fraction (LVEF). Left bundle branch area pacing successfully achieved cardiac resynchronization in a patient with heart failure, complete left bundle branch block, and atrial tachycardia, increasing LVEF from 34% to 73% at 1 year.
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