Prescriptions and Ingredients for Controlled CC Bond Formation with Organometallic Reagents. New synthetic methods (5)

Merits and drawbacks of known carbon‐carbon linking procedures are outlined. Two novel methods are discussed in some detail: the copper‐catalyzed alkylation of Grignard reagents and reactions with allylpotassium compounds. Both methods provide a very efficient access to saturated, unsaturated, as well as functionally substituted hydrocarbons and moreover permit an astonishing degree of regio‐ and stereoselective control of olefin synthesis.