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A factor in normal chicken serum when added to heated or unheated immune turkey serum-antigen complexes caused fixation of guinea pig complement. The factor was labile at 56°, unstable at room or refrigerator temperatures but remained active for several weeks at —20°C It was found in the water insoluble fraction of serum and could be removed from diluted serum on kaolin.
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Brumfield et al. (1959) studied this question.
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