Key result
High TIMI score linked to ~5-fold more in-hospital adverse outcomes after primary PCI for STEMI.
Why the study?
Does a high TIMI risk score predict greater angiographic severity and worse in-hospital outcomes in STEMI patients undergoing primary PCI?
Observational (n=64)
Does a high TIMI risk score predict greater angiographic severity and worse in-hospital outcomes in STEMI patients undergoing primary PCI?
Absolute Event Rate: 31.3% vs 6.3%
p-value: p=0.01
A high TIMI risk score (≥5) correlates with more severe coronary artery disease and higher rates of adverse in-hospital outcomes in STEMI patients treated with primary PCI.
May aid prognostication in STEMI primary PCI; hypothesis-generating and should not yet change practice.
Background: The Thrombolysis In Myocardial Infarction (TIMI) risk score was developed as a bedside tool to stratify STEMI patients eligible for reperfusion by their mortality risk. The TIMI risk score has shown to provide good discrimination in predicting mortality at 30 days and even up to 365 days.Methods: By purposive sampling a total of 64 consecutive patients were considered. Coronary artery disease severity was assessed by Vessels Score. The in-hospital adverse outcomes looked for were heart failure, cardiogenic shock, ventricular arrhythmia, re-infarction, stroke and death. Study subject was divided into two groups on the basis of TIMI risk score. In group I - patients with low TIMI risk score (0- 4); in group II - Patients with high TIMI risk score (≥5).Results: Multi vessel involvement were less in low TIMI group 1 (3.1%) but much greater (p<0.05) in high TIMI group 9 (28.1%). Adverse outcome was present 10(31.3%) in high TIMI group and 2(6.3%) in low TIMI group (p=0.01).Conclusion: High TIMI risk score was associated with more adverse in hospital outcome in patients with STEMI who underwent primary PCI. This study also demonstrated that the TIMI risk score carried a significant positive correlation with the coronary artery disease severity.Cardiovasc. j. 2018; 10(2): 135-139
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Howlader et al. (2018) conducted an observational in STEMI undergoing primary PCI (n=64). High TIMI risk score (≥5) vs. Low TIMI risk score (0-4) was evaluated on In-hospital adverse outcomes (heart failure, cardiogenic shock, ventricular arrhythmia, re-infarction, stroke and death) (p=0.01). A high TIMI risk score (≥5) was associated with a significantly higher rate of in-hospital adverse outcomes compared to a low score (31.3% vs 6.3%; p=0.01) in STEMI patients undergoing primary PCI.
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