Key result
Surgical excision of a renal nodule in metastatic esophageal adenocarcinoma reveals rare primary epithelioid hemangioendothelioma.
Case Report (n=1)
Primary renal epithelioid hemangioendothelioma is an extremely rare vascular tumor that can present as an isolated renal nodule and must be differentiated from metastatic carcinoma.
Isolated renal nodules in metastatic cancer require histologic differentiation from rare primaries; leaves open optimal management strategies for renal epithelioid hemangioendothelioma.
Epithelioid hemangioendothelioma is a rare vascular tumor with intermediate biologic behavior and metastatic potential. Primary renal epithelioid hemangioendothelioma is extremely rare and we present the second report of this rare tumor in an interesting clinical scenario. A 59-year-old male with established history of widely metastatic high grade esophageal adenocarcinoma was found to have an isolated renal nodule on a followup computed tomography (CT) scan. Surgical excision, with the suspicion of metastatic carcinoma, and subsequent pathologic examination revealed an epithelioid hemangioendothelioma. The various differential diagnoses and use of morphological clues and immunohistochemistry are discussed.
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Roy et al. (2012) conducted a case report in Primary renal epithelioid hemangioendothelioma (n=1). Surgical excision was evaluated. Surgical excision of an isolated renal nodule in a 59-year-old male with metastatic esophageal adenocarcinoma revealed a rare primary renal epithelioid hemangioendothelioma.
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