Key result
Lung squamous cell carcinoma atypically metastasizes to the left apical endocardium.
Case Report (n=1)
No
This case report demonstrates a rare instance of lung squamous cell carcinoma metastasizing to the left ventricular endocardium, emphasizing the utility of echocardiography in detecting atypical cardiac metastases.
Echocardiography may detect rare endocardial metastases in lung cancer; leaves open whether targeted imaging improves staging or outcomes.
Cardiac metastasis usually appears in patients with disseminated tumor disease. Involvement of heart in malignancy is generally underestimated and found to be in up to 25% of post mortem patients who had died of cancer. Cardiac involvement in metastases is usually uncommon; however, it may present with tachycardia, arrhythmia, cardiomegaly, heart failure, dyspnoea, hypotension, and pulsus paradoxus. Right side of heart is commonly known to be involved and the order of frequency of malignancies to metastasize to layers of the heart is pericardium, myocardium and endocardium.
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Ete et al. (2015) conducted a case report in Squamous cell carcinoma of lung with cardiac metastasis (n=1). Palliative therapy was evaluated. A rare case of squamous cell carcinoma of the lung metastasized to the left side of the heart, atypically involving the endocardium in the apical region.
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