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(1) The results are given of trials with trypanocidal drugs in cases of human sleeping sickness in Northern Nigeria. (2) Of drugs in the melarsen group, melarsen itself proved to be most promising for further use in the field. (3) Melarsen oxide and MelB were found unsuitable for large-scale use in the absence of skilled supervision. (4) Pentamidine was found to exert a definite effect on cases with a moderae degree of C.S.F. change, and equals tryparsamide in this respect. (5) The combination of pentamidine and tryparsamide is the most satisfactory of the older forms of treatment and it may in time replace antrypoltryparsamide mixture.
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Duggan et al. (1951) studied this question.
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