Key result
Partial hepatectomy successfully treats a rare case of hepatic biphasic synovial sarcoma without recurrence.
Why the study?
Synovial sarcoma originating in the liver is extremely rare, with only 7 cases reported in the literature.
Case Report (n=1)
No
Synovial sarcoma of the liver is an extremely rare malignancy that requires a combination of histopathological, immunohistochemical, and cytogenetic assessment for accurate diagnosis.
Documents rare pediatric primary hepatic synovial sarcoma; extends 7 prior cases but leaves diagnostic and therapeutic approaches open.
BACKGROUND: Synovial sarcoma is a soft tissue sarcoma of temporarily unknown histologic origin with the ability for biphasic differentiation, occurring mostly in the vicinity of large joints of the extremities. Synovial sarcoma that originates in the liver is extremely rare. Only 7 cases have been reported in the domestic and international literature. CASE PRESENTATION: We report an 11-year-old female patient who underwent partial hepatectomy for a liver mass. Microscopically, she was diagnosed with hepatic biphasic synovial sarcoma. Cytogenetic examination revealed the fusion gene SS18-SSX1 (+), which confirmed the diagnosis. CONCLUSION: Synovial sarcoma of the liver is a rare malignancy that is difficult to diagnose. Confirmation of diagnosis is based on histopathological assessment combined with immunohistochemical staining and, if necessary, cytogenetic aids.
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Liang et al. (2022) conducted a case report in Hepatic biphasic synovial sarcoma (n=1). Partial hepatectomy was evaluated on Postoperative recovery and recurrence. Partial hepatectomy successfully treated a rare case of hepatic biphasic synovial sarcoma in an 11-year-old female, with no recurrence observed at follow-up.
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