Key result
Surgical resection and multimodal chemoradiotherapy treat a rare anterior mediastinal biphasic synovial sarcoma.
Case Report (n=1)
Primary mediastinal biphasic synovial sarcoma is an extremely rare entity that can be managed with surgical resection and multimodal adjuvant therapy.
Successful multimodal management in rare mediastinal synovial sarcoma adds to sparse case reports; leaves open optimal regimens and long-term outcomes.
Synovial sarcomas are most frequently observed in the extremities. Although synovial sarcomas are the third most common histological type of soft-tissue sarcomas of the extremities, primary mediastinal synovial sarcoma is extremely rare. Monophasic synovial sarcoma is the most commonly observed subtype. whereas the biphasic subtype is less common. We present our case which was diagnosed as biphasic synovial sarcoma located in the anterior mediastinum, which is considered to be a rare entity. The patient underwent surgical resection together with multimodal adjuvant radiotherapy and chemotherapy.
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Tezcan et al. (2012) conducted a case report in Primary intrathoracic biphasic synovial sarcoma (n=1). Surgical resection with multimodal adjuvant radiotherapy and chemotherapy was evaluated. A rare case of primary biphasic synovial sarcoma in the anterior mediastinum was treated with surgical resection and multimodal adjuvant radiotherapy and chemotherapy.
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