Key result
Two cases of unresectable primary mediastinal synovial sarcoma treated with radiotherapy and chemotherapy developed complete esophageal obstruction due to progressive disease.
Case Report (n=2)
Primary mediastinal synovial sarcoma is an extremely rare and aggressive disease that can progress to cause esophageal obstruction despite chemoradiotherapy.
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Esophageal obstruction may complicate chemoradiotherapy-treated mediastinal synovial sarcoma; leaves open optimal strategies for this rare entity.
Synovial sarcoma is the third most common histological type of extremity soft tissue sarcoma. However, primary mediastinal synovial sarcoma is extremely rare. We present 2 cases of unresectable primary mediastinal synovial sarcoma. The radiographic imaging of our present cases was characteristic of a heterogeneously enhancing mass. They were treated with radiotherapy and chemotherapy. However, there was complete obstruction of esophagus resulting from progressive diseases. The radiographic findings and treatment were discussed.
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Kaira et al. (2008) conducted a case report in Primary mediastinal synovial sarcoma (n=2). Radiotherapy and chemotherapy was evaluated on Complete obstruction of esophagus resulting from progressive diseases. Two cases of unresectable primary mediastinal synovial sarcoma treated with radiotherapy and chemotherapy developed complete esophageal obstruction due to progressive disease.
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