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The urinary excretion of adrenaline and noradrenaline in normal and cold-adapted rats was investigated. The level of noradrenaline was found to be 15 times higher than that of adrenaline in both normal and cold-adapted animals. A fivefold increase of these two amines was observed in animals adapted to cold. A study in adrenalectomized rats indicated that this increased excretion of adrenaline in cold-adapted animals originated from the adrenals, whereas the increase in noradrenaline would have been secreted outside these glands.
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LeBlanc et al. (1961) studied this question.
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