Key result
Duodenal biopsy reveals pathognomonic adenovirus particles in a terminal AIDS patient with intractable diarrhea.
Case Report (n=1)
Adenovirus infection of the duodenal mucosa can be a cause of intractable diarrhea in patients with terminal AIDS, diagnosable via electron microscopy.
Answers are grounded in this paper and cite their sources.
Adenovirus may cause refractory diarrhea in terminal AIDS; single case leaves open prevalence, diagnostics, and management.
Intractable diarrhea in a 40-year-old woman with terminal acquired immunodeficiency syndrome resulted from adenovirus infection of the duodenal mucosa. Electron microscopic examination of a duodenal biopsy specimen performed because of clinical suspicion of cryptosporidiosis or microsporidiosis showed pathognomonic viral particles in the nuclei of mucosal epithelium. Extensive sloughing of damaged mucosal cells may have contributed to the diarrhea, for which no other cause was found during either pathologic or microbiologic analysis.
No takes yet. Share an insight, caveat, or question.
Yi et al. (1994) conducted a case report in Acquired immunodeficiency syndrome (AIDS) with intractable diarrhea (n=1). Adenovirus infection of the duodenal mucosa was evaluated on Identification of the cause of intractable diarrhea. Electron microscopic examination of a duodenal biopsy in a 40-year-old woman with terminal AIDS and intractable diarrhea revealed pathognomonic adenovirus particles in the mucosal epithelium.
Synapse has enriched 10 related papers. Consider them for comparative context: