Key result
Pre-workout supplement use before strenuous exercise linked to cardiac ischemia in a 33-year-old female.
Why the study?
Despite increasing popularity, the safety profile of pre-workout supplements is not well understood, and undisclosed proprietary blends create safety regulation difficulties.
Case Report (n=1)
This case highlights the potential risk of cardiac ischemia associated with pharmacologically active ingredients in pre-workout supplements.
Pre-workout supplements may warrant inquiry in acute chest pain with troponin rise; this case leaves open causal risks of specific ingredients.
The popularity of pre-workout supplements is rising amongst professional athletes and fitness enthusiasts. Despite increased usage, the safety profile of pre-workout supplements is likely to be not well understood. Additionally, many different brands use various undisclosed proprietary blends of active ingredients creating safety regulation difficulties. This lack of oversight could prove unsafe for certain patients. This patient MK is a 33-year-old healthy housewife who presented with central chest tightness, pre-syncope and mild dyspnoea to the emergency department via ambulance. The presentation was in the context of recent strenuous exercise and ingestion of a pre-workout supplement (Alpha Lean-7). Most striking in her presentation was a troponin rise of 50 ng/L, while not very high it is unusual given her lack of cardiac risk factors. She had a 3-day uneventful admission with a downtrending troponin prior to discharge. This case highlights the possible dangers of pharmacologically active ingredients in pre-workout supplements.
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Samuel Sherng Young Wang (2019) conducted a case report in Cardiac ischaemia (n=1). Pre-workout supplement (Alpha Lean-7) was evaluated on Cardiac ischaemia (troponin rise). Ingestion of a pre-workout supplement (Alpha Lean-7) prior to strenuous exercise was associated with cardiac ischaemia and a troponin rise of 50 ng/L in a healthy 33-year-old female.
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