Synthesis and Screening of Phosphodiesterase 5 Inhibitory Activity of Fused and Isolated Triazoles Based on Thieno[2,3‐d]pyrimidines

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Novel fused and isolated triazoles based on thieno[2,3‐d]pyrimidines were synthesized starting from 2‐aminothiophene ester and structurally confirmed by spectral and analytical data. The synthesized triazolo compounds were screened for their phosphodiesterase 5 inhibitory activity and showed encouraging activity than did sildenafil as a reference drug.