Key result
Microwave ablation creates larger lesions with increased power and duration, reaching ~12 mm depths.
Population
Blood superfused ovine tissue model to simulate endocardial ablation
Design
Preclinical
Authors
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Supports feasibility of deep lesions with microwave ablation in tissue models; leaves open translation to clinical arrhythmia treatment.
p-value: p=<0.05
Microwave ablation in an ovine tissue model demonstrates the ability to create deep, transmural lesions, though deep penetration requires large lesion volumes.
Thomas et al. (1999) studied Arrhythmias. Microwave ablation was evaluated on Lesion size (p=<0.05). Microwave ablation produced lesions that increased in size with increasing duration of exposure and forward power (P < 0.05), achieving depths of 11.9 mm at 80 W.
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