Key result
Confirmed EV-D68 infection is linked to severe illness requiring hospitalization in ~94% of cases.
Observational (n=220)
Surveillance in Wales highlights a significant burden of EV-D68 infection in young children, with high rates of hospitalization and severe respiratory or neurological complications.
High EV-D68 hospitalization and ICU rates support targeted pediatric surveillance; leaves open risk stratification and generalizability.
Since 7 June 2018, an enterovirus D-68 (EV-D68) season (the third since 2015) is ongoing in Wales, with 114 confirmed cases thus far. Median age of the 220 cases since 2015 is 2.5 years (2.5 years in intensive care cases), 94% were hospitalised, 17% (n = 38) in intensive care. All had respiratory symptoms; bronchiolitis symptoms were reported in 60 cases, severe respiratory symptoms in 23 and acute flaccid myelitis in two cases.
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Cottrell et al. (2018) conducted an observational in Enterovirus D68 (EV-D68) infection (n=220). Enterovirus D68 (EV-D68) infection was evaluated on Hospitalization. Prospective surveillance of 220 confirmed EV-D68 cases in Wales from 2015 to 2018 revealed that 94% required hospitalization and 17% were admitted to intensive care.
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