Why the study?
Pulmonary hypertension is reported as a common accompaniment of chronic kidney disease often without evident secondary causes, prompting investigation into its prevalence and risk factors in stage 5 CKD.
What is the prevalence and what are the risk factors of pulmonary hypertension in patients with stage 5 chronic kidney disease?
Population
100 stage 5 CKD patients (50 on maintenance hemodialysis and 50 on conservative management)
Comparison
Maintenance hemodialysis vs conservative management
Design
Cross-sectional study
Key result
Stage 5 chronic kidney disease was associated with an 89% prevalence of pulmonary hypertension, with significant associations noted for maintenance hemodialysis and dialysis vintage.
Authors
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PH prevalence of 89% in stage 5 CKD supports echocardiographic evaluation; leaves open whether screening alters outcomes in this population.
Cross-Sectional (n=100)
What is the prevalence and what are the risk factors of pulmonary hypertension in patients with stage 5 chronic kidney disease?
There is a very high prevalence of pulmonary hypertension (89%) in stage 5 CKD patients, which is better detected using a combination of modified Bernoulli's formula and pulmonary artery acceleration time.
Sankaranarayanan et al. (2022) conducted a cross-sectional in Stage 5 Chronic Kidney Disease (n=100). Stage 5 Chronic Kidney Disease was evaluated on Prevalence of pulmonary hypertension. Stage 5 chronic kidney disease was associated with an 89% prevalence of pulmonary hypertension, with significant associations noted for maintenance hemodialysis and dialysis vintage.