Key result
Spirits consumption linked to ~6-fold greater MI risk, while red wine shows no association.
Why the study?
Does the consumption of red wine or spirits affect the risk of acute myocardial infarction in males under 60?
Population
118 Dutch males under sixty years of age, assessed before and after acute myocardial infarction in a…
Comparison
Consumption of different types of alcoholic… vs Controls (males without MI)
Design
Case-control
Authors
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Should not yet change alcohol advice for MI prevention; leaves open differential effects of red wine versus spirits.
Case-Control (n=118)
Does the consumption of red wine or spirits affect the risk of acute myocardial infarction in males under 60?
Odds Ratio: 0.4
p-value: p=0.17
The apparent protective effect of red wine against MI may be confounded by psychological factors, whereas spirits consumption appears to be a strong independent risk factor.
Cleophas et al. (1996) conducted a case-control in Acute myocardial infarction (n=118). Red wine and spirits consumption vs. Controls was evaluated on Acute myocardial infarction (OR 0.4, p=0.17). After adjusting for confounders, red wine consumption was not significantly associated with MI risk (OR 0.4, P=0.17), whereas spirits consumption significantly increased the risk (OR 6.0, P=0.01).
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