Key result
Routine confidence intervals can combat the scientific decline effect by exposing unreliable or missed effects.
Design
Other
Authors
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May warrant CI reporting in CV trials to bound effects; leaves open reversal of decline effect without broader reforms.
Routine use of confidence intervals, adjusted for multiple comparisons, can help combat the scientific decline effect by providing bounds on true effect sizes.
David M. Groppe (2016) studied this question. Confidence intervals was evaluated. Routine use of confidence intervals can combat the scientific decline effect by revealing when statistically significant effects are too small to be reliable or when large effects are missed.