Key result
Absorption of ≥500 ml of irrigating fluid during transurethral resection of the prostate was associated with an increased risk of acute myocardial infarction.
Why the study?
Do operative factors such as irrigating fluid absorption and blood loss during TURP affect the long-term incidence of acute myocardial infarction?
Cohort (n=846)
Do operative factors such as irrigating fluid absorption and blood loss during TURP affect the long-term incidence of acute myocardial infarction?
Answers are grounded in this paper and cite their sources.
Operative factors during TURP, specifically high irrigating fluid absorption combined with low blood loss, are associated with a significantly increased long-term risk of acute myocardial infarction.
We studied the association between the operative course of transurethral resection of the prostate (TURP) and the morbidity of acute myocardial infarction (AMI) in a cohort comprising 846 patients who underwent this operation between 1983 and 1992. Up to the end of 1993, a total of 69 patients had developed AMI, of which 10 patients had a reinfarction. The relative risk associated with absorption of 500 ml or more of the irrigating medium during surgery was 1.6 [95% confidence interval (CI) = 0.9-3.0] for a first-time AMI after TURP, 6.1 (95% CI = 1.8-20.7) for a reinfarction, and 2.2 (95% CI = 1.3-3.9) for a first-time or a reinfarction combined. A blood loss of 275 ml or more was associated with a decreased relative risk (RR = 0.4; 95% CI = 0.2-0.8) of a first-time AMI after TURP. Patients who lost less than 275 ml of blood and absorbed 500 ml or more of irrigating fluid during surgery had 4.4 times the risk of having an acute myocardial infarction (RR = 4.4; 95% CI = 1.7-11.8). These results appear to indicate that the operative course of TURP is important to the development of AMI over an extended period of time.
No takes yet. Share an insight, caveat, or question.
Hahn et al. (1996) conducted a cohort in Transurethral resection of the prostate (TURP) (n=846). Absorption of ≥500 ml of irrigating medium during surgery vs. Absorption of <500 ml of irrigating medium was evaluated on First-time or reinfarction acute myocardial infarction combined (RR 2.2, 95% CI 1.3-3.9). Absorption of ≥500 ml of irrigating fluid during transurethral resection of the prostate was associated with an increased risk of acute myocardial infarction.
Synapse has enriched 10 related papers. Consider them for comparative context: