Key result
Cardiac surgery in patients 80 and older carries similar hospital mortality to those 70 to 79.
Why the study?
Do operative and hospital outcomes differ between cardiac surgery patients aged 70-79 years and those aged 80 years or older?
Observational (n=445)
No
Do operative and hospital outcomes differ between cardiac surgery patients aged 70-79 years and those aged 80 years or older?
Cardiac surgery can be performed in octogenarians with low operative mortality, though they experience higher rates of postoperative renal failure and non-home discharge compared to septuagenarians.
Age-specific variables in elderly cardiac surgery warrant cautious use; leaves open need for prospective outcome validation.
Background: To establish which variables between cardiac surgery pts aged 70 - 79 years and 80 years or over are individually different for age group status. Methods: Group 1, 70 - 79 years, n = 351 and Group 2, age 80 or over n = 94. Demographics, operative and hospital outcomes were identified and EuroSCORE (ES) scores applied. Logistic regression uni- and mul-tivariate analysis was used to detect pre- and postop-erative variables which might be independently different between the Groups. Results: Difference (p < 0.05) was noted in (higher in Group 2) patients with CHF, NYHA class, atrial fibrillation, aortic valve disease, both ES algorithms. Group 2 pts had lower ejection fraction and less coronary artery disease. Group 1 had more pts with diabetes. Operative mortality was low (1.7% total) with no difference between the Groups. Length of stay in the postoperative intensive care unit and total hospitalization was equal but Group 2 pts needed more often prolonged stay. Group 2 pts had more postoperative renal failure (p = 0.002) and were more often not discharged home (p = 0.03). Hospital mortality did not reach statistical significance (Group 1 18/5.2%, Group 2 10/10.7%, p = 0.06). Univariate analysis detected 12 pre- and post-operative variables which identified Group status. Multivariate analysis using univariate results detected only diabetes (for Group 1 status) and additive ES (for Group 2 status) to be independently different between the Groups. Conclusions: Elderly pts may be operated with low operative and hospital mortality. Only diabetes and additive ES (=comorbidities) were independently different between the Groups.
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Jyrala et al. (2012) conducted an observational in Cardiac surgery (n=445). Age 80 years or older vs. Age 70 to 79 years was evaluated on Hospital/30-day mortality (OR 2.09, 95% CI 1.00-4.37, p=0.06). Patients aged 80 years or older undergoing cardiac surgery had similar hospital mortality compared to those aged 70 to 79 years, with only diabetes and additive EuroSCORE independently differentiating the groups.
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