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November 1, 2005Archives of Surgery

Cardiac Surgery in Octogenarians

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Key result

Octogenarians undergoing coronary artery bypass grafting or valve surgery had a higher risk of death compared with younger patients (RR 1.72; 95% CI 1.52-1.83).

Why the study?

Does being an octogenarian increase the risk of mortality and morbidity in patients undergoing coronary artery bypass grafting or valve surgery?

Population

7,726 consecutive patients undergoing coronary artery bypass grafting or valve surgery, including 522…

Comparison

Age ≥80 years undergoing coronary artery bypass… vs Age <80 years undergoing coronary artery bypass…

Design

Cohort

Follow-up

hospitalization

Authors

WJW M JohnsonNational Center for Disease Control

Discussion

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Implication

Age independently predicts higher morbidity and mortality after cardiac surgery; leaves open refined selection criteria for octogenarians.

Study Design

Type

Cohort (n=7,726)

Multicenter

No

Structured PICO

Does being an octogenarian increase the risk of mortality and morbidity in patients undergoing coronary artery bypass grafting or valve surgery?

P
Population
7,726 patients undergoing coronary artery bypass grafting or valve surgery, including 522 octogenarians, evaluated for in-hospital morbidity and mortality.
E
Exposure
Age ≥80 years (octogenarians) undergoing coronary artery bypass grafting or valve surgery
C
Comparator
Age <80 years (nonoctogenarians) undergoing coronary artery bypass grafting or valve surgery
O
Outcome
9 main outcomes: mortality, length of hospital stay, gastrointestinal tract complications, neurologic complications, pulmonary complications, renal complications, return to intensive care unit, intraoperative complications, and reoperation to treat bleedinghard clinical

Main Result

Relative Risk: 1.72 (95% CI 1.52–1.83)

Octogenarians undergoing CABG or valve surgery have significantly higher mortality and morbidity compared to younger patients, even after adjusting for confounding variables.

Cite This Study

W M Johnson (2005) conducted a cohort in Coronary artery bypass grafting or valve surgery (n=7,726). Age ≥ 80 years (Octogenarians) vs. Age < 80 years (Nonoctogenarians) was evaluated on Mortality (RR 1.72, 95% CI 1.52-1.83). Octogenarians undergoing coronary artery bypass grafting or valve surgery had a higher risk of death compared with younger patients (RR 1.72; 95% CI 1.52-1.83).

synapsesocial.com/papers/6a428c47c97252f2d147be3ehttps://doi.org/10.1001/archsurg.140.11.1089

Topics

Valvular heart disease
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Quality of Life in Octogenarians After Open Heart Surgery1995 · 71 citations
  2. 2Open-Heart Surgery in Octogenarians1988 · 300 citations
  3. 3Cost-Effectiveness of Coronary Artery Bypass Surgery in Octogenarians1998 · 64 citations
  4. 4Survival After Coronary Revascularization in the Elderly2002 · 349 citations
  5. 5Changes in Mortality after Myocardial Revascularization in the Elderly: The National Medicare Experience1994 · 155 citations