Key result
Preoperative mild-to-moderate renal impairment (GFR 45-59 ml/min/1.73 m2) was associated with a higher rate of postoperative acute kidney injury compared to GFR >60 ml/min/1.73 m2 (38.7% vs 23.9%).
Why the study?
Does mildly reduced baseline kidney function (eGFR 45-59 ml/min/1.73 m2) increase the risk of acute kidney injury in patients undergoing cardiac surgery compared to preserved kidney function?
Cohort (n=1,126)
Does mildly reduced baseline kidney function (eGFR 45-59 ml/min/1.73 m2) increase the risk of acute kidney injury in patients undergoing cardiac surgery compared to preserved kidney function?
Answers are grounded in this paper and cite their sources.
Patients with mildly reduced baseline kidney function (eGFR 45-59 ml/min/1.73 m2) have a substantially higher rate of acute kidney injury following cardiac surgery compared to those with preserved function.
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Bg et al. (2015) conducted a cohort in Cardiac surgery (n=1,126). Preoperative GFR 45-59 ml/min/1.73 m2 vs. Preoperative GFR >60 ml/min/1.73 m2 was evaluated on Acute kidney injury (AKI) in the early postoperative period. Preoperative mild-to-moderate renal impairment (GFR 45-59 ml/min/1.73 m2) was associated with a higher rate of postoperative acute kidney injury compared to GFR >60 ml/min/1.73 m2 (38.7% vs 23.9%).
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