Key result
Dipyridamole thallium-201 scintigraphy detects microvascular dysfunction in ~69% of vasospastic angina patients with normal coronaries.
Why the study?
Does dipyridamole thallium-201 scintigraphy reveal microvascular dysfunction in patients with vasospastic angina and normal coronary arteries?
Population
16 patients with vasospastic angina and normal coronary arteries
Design
Cross-sectional
Authors
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Suggests microvascular dysfunction in vasospastic angina; hypothesis-generating and should not yet change practice.
Observational (n=16)
Does dipyridamole thallium-201 scintigraphy reveal microvascular dysfunction in patients with vasospastic angina and normal coronary arteries?
In patients with vasospastic angina and normal coronary arteries, reversible perfusion defects on dipyridamole scintigraphy suggest microvascular dysfunction contributes to abnormal perfusion.
Fujita et al. (2000) conducted an observational in Vasospastic angina and nearly normal coronary arteries (n=16). Dipyridamole thallium-201 scintigraphy was evaluated on Reversible thallium-201 defects. Dipyridamole thallium-201 scintigraphy demonstrated reversible defects in 11 of 16 patients with vasospastic angina and normal coronary arteries, indicating microvascular dysfunction.