Key result
Group A rotavirus affects ~8% of acute gastroenteritis outpatients, predominantly the G9P[8] strain.
Why the study?
Group A human rotaviruses cause substantial annual pediatric mortality, prompting the need to understand their epidemiological characteristics and genetic evolution in China.
Population
2007 fecal samples from hospital outpatients with acute gastroenteritis from four cities in Hubei Province
Design
Sentinel surveillance study
Authors
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Supports continued rotavirus strain surveillance in Hubei; leaves open implications for local vaccine performance.
Observational (n=2,007)
Yes
The study provides epidemiological and evolutionary data on rotavirus strains in Hubei, China, highlighting the predominance of G9P[8] and the emergence of G2P[4].
Zhang et al. (2022) conducted an observational in Acute gastroenteritis (n=2,007). Group A human rotavirus (RVA) was evaluated on RVA positivity by real-time RT-PCR. Group A rotavirus was detected in 7.62% of outpatients with acute gastroenteritis in Hubei, China, with G9P[8] as the predominant strain and G2P[4] prevalence increasing rapidly since 2014.
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