The bile acid pool was found to be ca. 50 mumoles/100 g body wt in male and female rats maintained on standard laboratory chow and ca. 30 mumoles/100 g body wt in those maintained on a standard semisynthetic diet. The distribution of bile acids within the pool was similar in plasma, liver, and intestinal tract, except for a higher concentration of deoxycholic acid in the intestinal tract. Sex differences in bile acid composition were found to be influenced by the dietary regimen of the animals.
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Fisher et al. (1976) studied this question.
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