Key result
Acute capsaicin fails to increase time to exhaustion compared to placebo in runners.
Why the study?
To investigate the effect of acute capsaicin supplementation on time to exhaustion, physiological responses, and energy systems contribution during a continuous high-intensity exercise session in runners.
Does acute capsaicin supplementation improve time to exhaustion in recreationally-trained runners during high-intensity continuous exercise?
RCT (n=15)
Double-blind
randomized
Does acute capsaicin supplementation improve time to exhaustion in recreationally-trained runners during high-intensity continuous exercise?
Standardized Mean Difference: -0.28
Absolute Event Rate: 654.28% vs 709.2%
p-value: p=0.462
Acute capsaicin supplementation does not improve time to exhaustion or alter physiological responses during high-intensity continuous exercise in runners.
Acute capsaicin fails to extend time to exhaustion or alter responses in continuous high-intensity running; challenges ergogenic effects seen in intermittent protocols and leaves modality-specific benefits open.
To investigate the effect of acute capsaicin (CAP) supplementation on time to exhaustion, physiological responses and energy systems contribution during continuous high-intensity exercise session in runners. Fifteen recreationally-trained runners completed two randomized, double-blind continuous high-intensity exercises at the speed eliciting 90% V̇O2peak (90% s V̇O2peak), 45 minutes after consuming capsaicin or an isocaloric placebo. Time to exhaustion, blood lactate concentration, oxygen consumption during and 20-min post-exercise, energy systems contribution, time to reach V̇O2peak, heart rate and the rate of perceived exertion (RPE) were evaluated. There was no significant difference between conditions for time to reach V̇O2peak (CAP:391.71±221.8 vs. PLA:298.20±174.5 sec, ES:0.58, p=0.872), peak lactate (CAP:7.98±2.11 vs. PLA:8.58±2.15 µmol, ES:−0.28, p=0.257), time to exhaustion (CAP:654.28±195.44 vs. PLA:709.20±208.44 sec, ES:−0.28, p=0.462, end-of-exercise heart rate (CAP:177.6±14.9 vs. PLA:177.5±17.9 bpm, ES:−0.10, p=0.979) and end-of-exercise RPE (CAP: 19±0.8 vs. PLA: 18±2.4, ES: 0.89, p=0.623). In conclusion, acute CAP supplementation did not increase time to exhaustion during high-intensity continuous exercise nor alter physiological responses in runners.
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Padilha et al. (2020) conducted an RCT in Recreationally-trained runners (n=15). Capsaicin vs. Isocaloric placebo was evaluated on Time to exhaustion (ES -0.28, p=0.462). Acute capsaicin supplementation did not significantly increase time to exhaustion compared to placebo in runners (654.28 vs 709.20 sec; p=0.462).
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