Key result
TRIM5α oligomerizes into trimers to potentially interact with threefold pseudosymmetrical structures on retroviral capsids.
Authors
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TRIM5α trimerization may enable capsid recognition; leaves open whether this mechanism restricts retroviruses in vivo.
Mische et al. (2005) studied this question. TRIM5α was evaluated. The retrovirus restriction factor TRIM5α oligomerizes into trimers, potentially allowing it to interact with threefold pseudosymmetrical structures on retroviral capsids.
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