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Optic nerve colobomas are rare congenital anomalies that result from failure of the superior end of the embryonic fissure to close. Ocular abnormalities associated with optic nerve colobomas include the presence of posterior lenticonus, posterior embryotoxon, optic nerve pit, optic sheath cyst, and remnants of the hyaloid artery.1We describe a patient with a peripapillary subretinal neovascular membrane associated with an isolated optic nerve coloboma. Report of a Case. —A 48-year-old man who previously had 20/20 OU visual acuity complained of blurred vision in his right eye of 1 month's duration. Best corrected visual acuity was 20/50 OD and 20/20 OS. The anterior segments of both eyes were normal. Ophthalmoscopic examination of the right eye revealed an isolated optic nerve coloboma. The optic nerve was mildly pale, completely excavated, and approximately twice larger than the left in diameter. The retinal vessels entered and exited from the borders and coalesced
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John R. Dailey (1993) studied this question.
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