Key result
Modified single-patch repair for complete atrioventricular canal defect shows 0% in-hospital and midterm mortality.
Why the study?
This study aimed to evaluate short- and midterm outcomes following complete atrioventricular canal defect repair using a single-patch technique.
Observational (n=30)
No
The modified single-patch technique for complete atrioventricular canal defect repair in children is safe, with 0% mortality at 4 years, though patients without Down syndrome have a higher risk of late moderate mitral regurgitation.
Zero mortality supports technique safety in children; leaves open whether absence of Down syndrome increases late mitral regurgitation risk.
BACKGROUND: This study aimed to present the short- and midterm outcomes after complete atrioventricular canal defect (CAVC) repair using a single-patch technique. METHODS: This study included 30 children who underwent surgical correction of the CAVC using a single-patch technique. RESULTS: The median age of the patients was 5.7 months (interquartile range [IQR], 5.0-7.5 months), and 23 patients (76.7%) had type A CAVC. Fourteen patients (46.7%) were female and 17 (56.7%) had been diagnosed with Down syndrome. The in-hospital mortality rate was 0%. No deaths were observed during a median follow-up of 4 years (IQR, 3.5-5.0 years). Patients without Down syndrome were associated with late moderate mitral regurgitation (MR) (p=0.02). Late MR less than moderate degree was observed in 96.6%, 78.5%, and 50% of patients after 2, 4, and 5 years of follow-up, respectively, while late tricuspid valve regurgitation less than moderate degree was observed in 96.7%, 85.9%, and 59.0% of patients after 2, 4, and 6 years of follow-up, respectively. After a median follow-up of 4 years, only one patient had required surgical repair of a left ventricular outflow tract obstruction, which occurred 26 months after the first operation. Multivariable logistic regression analysis adjusted for the type of CAVC, sex, Down syndrome, age, and weight revealed that the absence of Down syndrome was a risk factor for late moderate MR (MR-2) (odds ratio, 0.05; 95% confidence interval, 0.006-0.50; p=0.01). CONCLUSION: A single-patch technique for CAVC surgical repair is a safe method with acceptable short- and midterm results.
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Samanidis et al. (2023) conducted an observational in Complete atrioventricular canal defect (CAVC) (n=30). Modified single-patch technique was evaluated on In-hospital mortality. Surgical repair of complete atrioventricular canal defect using a modified single-patch technique resulted in 0% in-hospital and midterm mortality, with acceptable short- and midterm outcomes.
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