Key result
Prinzmetal angina carries a 39% risk of MI or sudden death within months of onset.
A literature review of Prinzmetal angina highlights a high risk of severe complications, with a 39% combined incidence of myocardial infarction and sudden death.
Early reports link Prinzmetal angina to high short-term MI or death risk; leaves open whether contemporary therapies alter prognosis in prospective data.
Prinzmetal angina is a clinical-electrocardiographic syndrome characterized by attacks of angina pectoris unrelated to exercise and occurring frequently after meals or during the night. They last minutes to hours, often with a predictable daily pattern, and show a pathognomonic ECG consisting of ST segment elevation (rather than depression) during the attack, in the leads facing the region of myocardial ischemia.1Myocardial irritability and conduction disturbances are common during the attack. A review of the accessible literature shows that at least 111 cases have been reported.1-44Myocardial infarction and death are frequent complications. Of the 90 patients in whom pertinent information was given, 22 developed acute myocardial infarction1,4,5,7,8,10,13,20,32,35,36within months after the onset of attacks was stated, with one subsequent death20; 13 others died suddenly, often within months after onset1,3,6,14,16,22,23,27,29,36-a combined incidence of 39%. In 21 of the 23 patients studied by selective coronary arteriography,
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Lamberto G. Bentivoglio (1974) conducted a review in Prinzmetal angina (n=111). Bypass Surgery was evaluated on Acute myocardial infarction or sudden death. A literature review of patients with Prinzmetal angina found a 39% combined incidence of acute myocardial infarction or sudden death within months of symptom onset.
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