Key result
Blood pressure variability is an independent determinant of hypertensive end-organ damage, and combination therapies may synergistically reduce this variability to provide organ protection.
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Alex F. Chen (2008) conducted an editorial in Hypertension. Antihypertensive therapy (hydrochlorothiazide-nifedipine combination) was evaluated. Blood pressure variability is an independent determinant of hypertensive end-organ damage, and combination therapies may synergistically reduce this variability to provide organ protection.
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