Key result
Aortic valve repair or valve-sparing aortic root surgeries significantly decreased aortic regurgitation (P<0.001) and improved ejection fraction, with 5-year freedom from reoperation of 81%.
Why the study?
Do aortic valve repair or valve-sparing aortic root surgeries improve aortic regurgitation and left ventricular function in patients with aortic aneurysm or dissection?
Cohort (n=110)
Do aortic valve repair or valve-sparing aortic root surgeries improve aortic regurgitation and left ventricular function in patients with aortic aneurysm or dissection?
p-value: p=<0.001
Valve-sparing aortic root surgeries and aortic valve repair provide acceptable mid-term freedom from reoperation and significant improvements in left ventricular function for patients with aortic aneurysm or dissection.
May support valve-sparing repair in aortic aneurysm or dissection; leaves open need for randomized confirmation of durability.
INTRODUCTION: Valve-reimplantation and remodelling techniques used in aortic reconstruction provide successful early, mid, and long-term results. We present our early and late-term experience with 110 patients with aortic regurgitation (AR) who underwent aortic valve repair (AVr) or valve-sparing aortic root surgeries (VSARS) due to aortic dissection or aortic aneurysm. METHODS: Nine hundred eighty-two patients who underwent aneurysm or dissection surgery and aortic valve surgery between April 1997 and January 2017 were analysed using the patient database. A total of 110 patients with AR who underwent AVr or VSARS due to aortic dissection or aortic aneurysm were included in the study. RESULTS: In the postoperative period, a decrease was observed in AR compared to the preoperative period (P<0.001); there was an increase in postoperative ejection fraction (EF) compared to the preoperative values (P<0.005) and a significant decrease in postoperative left ventricle diameters compared to the preoperative values (P<0.001). Kaplan-Meier analysis revealed one, two, four, and five-year freedom from moderate-severe AR as 95%, 91%, 87%, and 70%, respectively. Freedom from reoperation in one, two, and five years were 97.9%, 93.6%, and 81%, respectively. Eight patients (7.4%) underwent AVr during follow-up. Out of the remaining 100 patients, 13 (12%) had minimum AR, 52 (48%) had 1st-2nd degree AR, and 35 (32%) had 2nd-3rd degree AR during follow-up. CONCLUSION: For the purpose of maintaining the native valve tissue, preserving the EF and the left ventricular end-diastolic diameter, valve-sparing surgeries should be preferred for appropriate patients.
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Yiğit et al. (2020) conducted a cohort in Aortic aneurysm or aortic dissection with aortic regurgitation (n=110). Aortic valve repair (AVr) or valve-sparing aortic root surgeries (VSARS) was evaluated on Postoperative aortic regurgitation (AR) severity compared to preoperative period (p=<0.001). Aortic valve repair or valve-sparing aortic root surgeries significantly decreased aortic regurgitation (P<0.001) and improved ejection fraction, with 5-year freedom from reoperation of 81%.
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