Key result
A nomogram incorporating IVIG resistance, delayed treatment, CRP, and NLR predicts coronary lesions with ~0.79 AUC.
Why the study?
Coronary artery lesions are the most important complications of Kawasaki disease and can lead to long-term cardiovascular sequelae, prompting the need to evaluate risk factors and predict lesion likelihood.
Does a nomogram incorporating clinical and laboratory variables predict coronary artery lesions in patients with Kawasaki disease?
Population
599 patients with Kawasaki disease
Comparison
Training set (n = 450) vs validation set (n = 149)
Design
Retrospective study
Authors
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May aid lesion risk stratification in Kawasaki disease; leaves open external validation before clinical adoption.
Observational (n=599)
Does a nomogram incorporating clinical and laboratory variables predict coronary artery lesions in patients with Kawasaki disease?
A nomogram based on IVIG resistance, delayed IVIG treatment, CRP, and neutrophil/lymphocyte ratio provides a reliable tool for predicting coronary artery lesions in Kawasaki disease.
Chen et al. (2023) conducted an observational in Kawasaki disease (n=599). Nomogram based on IVIG resistance, delayed IVIG treatment, C-reactive protein, and neutrophil/lymphocyte ratio was evaluated on Predictive efficiency of the nomogram (AUC). A nomogram incorporating IVIG resistance, delayed IVIG treatment, C-reactive protein, and neutrophil/lymphocyte ratio predicted coronary artery lesions with an AUC of 0.790 in the training set.
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