Key result
Agitated ECT sessions are linked to ~88% higher post-ECT plasma lactate levels versus nonagitated sessions.
Why the study?
Does increased plasma lactate correlate with post-ECT agitation, and does increasing succinylcholine dose prevent it?
Population
37 patients undergoing 245 consecutive ECT sessions
Comparison
Measurement of plasma lactate levels and… vs Nonagitated ECT sessions / standard…
Design
Cohort
Authors
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May link post-ECT agitation to lactate from inadequate blockade; leaves open whether higher succinylcholine doses reduce it.
Observational (n=37)
Does increased plasma lactate correlate with post-ECT agitation, and does increasing succinylcholine dose prevent it?
Absolute Event Rate: 4.77% vs 2.54%
p-value: p=< 0.05
Post-ECT agitation may be a manifestation of lactate-induced panic secondary to insufficient neuromuscular blockade, which can be mitigated by increasing the succinylcholine dose.
Auriacombe et al. (2000) conducted an observational in Patients undergoing electroconvulsive therapy (ECT) (n=37). Agitated ECT sessions vs. Nonagitated ECT sessions was evaluated on Mean post-ECT plasma lactate levels (p=< 0.05). Agitated ECT sessions were associated with significantly higher mean post-ECT plasma lactate levels compared to nonagitated sessions (4.77 vs 2.54 mmol/l, p < 0.05).
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