Key result
Hypertension is not linked to higher in-hospital complication risk in diabetic patients with acute MI.
Why the study?
To compare the incidence of in-hospital complications between diabetic normotensive and hypertensive diabetic patients presenting with acute myocardial infarction.
Does hypertension increase the risk of in-hospital complications in diabetic patients presenting with acute myocardial infarction?
Cohort (n=220)
No
Does hypertension increase the risk of in-hospital complications in diabetic patients presenting with acute myocardial infarction?
Absolute Event Rate: 14.5% vs 12.7%
p-value: p=0.326
Hypertension does not appear to significantly increase the risk of in-hospital complications among diabetic patients presenting with acute myocardial infarction.
Hypertension was not associated with higher in-hospital complications in diabetic acute MI patients; leaves open whether BP control modifies risk in this population.
Aim: To compare the incidence of in-hospital complications between diabetic normotensive and hypertensive diabetic patients presenting with acute myocardial infarction (MI) Methodology: This observational cohort study was conducted at National Institute of Cardiovascular Diseases Karachi from May 2019 to April 2020. We examined 220 diabetics with acute MI were included. 50% of the patients had high blood pressure and the rest had normal blood pressure. After enrollment in the study, selectees were observed for acute myocardial infarction complications in the hospital. Results: Most of the baseline characteristics were similar in both groups of patients. However, the hypertensive patients in the diabetes group had diabetes, high heart rate, and high blood pressure at reporting. The complication rates did not differ statistically between the two groups. The rates of complications occurred between diabetes and normotensive hypertension; Atrial fibrillation (AF) 15.5% vs 12.7% p = 0.194, respectively, ventricular tachycardia (LH) 14.5% vs 13.6%, AV block type-1 8.2% vs 7.3% p = 0.296, type2 AV block 2.7% vs 1.8% p = 0.352, complete heart block 11.8% vs 10% p = 0.313, acute congestive heart failure (CHF) 13.6% VS% 9.1 p = 0.137, left ventricular failure (LVF)19.1% vs 16.4% p = 0.259, cardiogenic shock (CS) 14.5% vs 10.9% p = 0.184, recurrent IM (Re-MI) 14.5% 10.9% p = 0.184 and mortality 14.5% vs 12.7 and% p = 0.326, respectively. Conclusion:It is concluded that diabetic patients with hypertensionhave not elevated risk of complications in the hospital after acute myocardial infarction.
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Akhtar et al. (2021) conducted a cohort in Acute myocardial infarction in diabetic patients (n=220). Hypertension vs. Normotensive (normal blood pressure) was evaluated on In-hospital death (p=0.326). Hypertension in diabetic patients presenting with acute myocardial infarction did not significantly increase the risk of in-hospital complications, including in-hospital death (14.5% vs 12.7%, p=0.326), compared to normotensive diabetic patients.
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