Key result
Positive ISAR scores predict a ~191% higher risk of unplanned 1-month readmission.
Why the study?
Do the ISAR and TRST screening tools predict unplanned readmission in patients over 75 years discharged from the emergency department?
Cohort (n=345)
No
Do the ISAR and TRST screening tools predict unplanned readmission in patients over 75 years discharged from the emergency department?
Hazard Ratio: 2.91 (95% CI 1.29–6.59)
p-value: p=0.010
The ISAR and TRST screening tools modestly predict unplanned readmission in elderly ED patients, but their high negative predictive values can safely identify patients who do not require further comprehensive geriatric assessment.
May aid readmission risk stratification in older adults; leaves open whether targeted interventions improve outcomes.
STUDY HYPOTHESIS: The Identification of Senior At Risk (ISAR) and the Triage Risk Stratification Tool (TRST) are the two most studied screening tools to detect high-risk patients for unplanned readmission after an emergency department (ED)-visit. Since their performance was unclear among ED-patients over 75 years, we evaluated their capacities to predict readmission at 1, 3, 6 and 12 months as well as their usefulness in avoiding unnecessary further comprehensive geriatric assessment (CGA) in negative screened patients. METHODS: Historical cohort study with systematic routine data collection of functional status, comorbid conditions and readmission rate of patients released home after an ED-visit between 2007 and 2009 at the Geneva University Hospitals. RESULTS: 345 patients were included (mean age 84y; 63% female). Readmission rates were 25%, 38%, 49%, and 60% at 1, 3, 6, and 12 months, respectively. Positive ISAR (≥2/6) and TRST (≥2/5) predicted modestly unplanned readmission at each time point (AUC range: 0.607-0.664). Prediction of readmission with ISAR or TRST was not modified after adjustment for variables significantly associated with readmission (being male, having poor functional or comorbid scores). In case of negative ISAR or TRST, their high negative predictive values (NPV) would safely allow avoiding 64 useless CGA (ISAR <2: 7/64 readmissions at 1 month). CONCLUSIONS: Both ISAR and TRST tools predicted modestly unplanned readmission after an ED-visit among patients over 75 years. Nevertheless, due to their low specificity and high NPV these screening tools are useful to select elderly ED-patients who can safely return home without any further CGA.
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Graf et al. (2012) conducted a cohort in Older patients discharged home after an emergency department visit (n=345). Positive Identification of Senior At Risk (ISAR ≥2/6) or Triage Risk Stratification Tool (TRST ≥2/5) score vs. Negative screening score (ISAR <2 or TRST <2) was evaluated on Unplanned readmission (new ED-visit or direct hospitalization) at 1 month (Adjusted HR 2.91, 95% CI 1.29-6.59, p=0.010). Positive ISAR (≥2/6) and TRST (≥2/5) scores modestly predicted unplanned readmission, with an ISAR ≥2 significantly increasing the risk of 1-month readmission (adjusted HR 2.91).
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