Key result
New experimental autoimmune myocarditis models provide valuable paradigms for human infection-induced autoimmune disease.
Highlights the utility of new experimental models of autoimmune myocarditis as paradigms for human disease and infection-induced autoimmunity.
May guide preclinical studies of infection-triggered autoimmunity; leaves open clinical translation pending validation.
There has been a resurgence of interest in immunologically-mediated heart disease, culminating in a recent meeting. This interest was sparked off by new experimental models of autoimmune myocarditis that have served two useful functions: first, as good models of human myocarditis and second, as paradigms of infection-induced autoimmune disease.
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Rose et al. (1991) studied this question. New experimental models of autoimmune myocarditis provide valuable representations of human myocarditis and serve as paradigms for infection-induced autoimmune disease.
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