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normal infants who were fed from the age of 2 months until 12 months old on either fresh cow's milk or a prepared formula which was introduced into the diet.At the end of the study the infants fed fresh cow's milk had a marginally lower haemoglobin level and mean cell volume; their serum iron concentration was lower at 6 months of age but not different from the normal group at 12 months.Occult blood tests were positive in most of the infants in both groups.Milk antibodies were found in four of the infants fed fresh milk and in one fed the formula when tested at 12 months of age.This study did not show a striking difference in the iron status of the normal babies fed fresh milk compared with those receiving formula, and the relevance of these studies to those carried out on infants with established iron-deficiency anaemia is conjectural.The possibility of individual suscept- iblity to fresh cow's milk in those with iron-deficiency anaemia cannot be excluded.It remains to be seen how common this condition is, and the exact way in which the enteropathy and the iron-deficiency develop and their inter- relationship require further elucidation.
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A 1973 study studied this question.
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