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January 1, 1991Biochemistry

A mutant of DNA polymerase I (Klenow fragment) with reduced fidelity

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Authors

SCSteven S. CarrollNational Maternity HospitalMCMarlon CowartAbbott (United Kingdom)SBStephen J. BenkovicScripps Research Institute

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Cite This Study

Carroll et al. (1991) studied this question.

synapsesocial.com/papers/6aa66abc163c608a823979e5https://doi.org/10.1021/bi00217a034
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1T5 DNA polymerase: structural--functional relationships to other DNA polymerases.1989 · 58 citations
  2. 2Kinetic mechanism of DNA polymerase I (Klenow)1987 · 353 citations
  3. 3Interaction of Escherichia coli DNA polymerase I with azidoDNA and fluorescent DNA probes: identification of protein-DNA contacts1990 · 59 citations
  4. 4Differential extension of 3′ mispairs is a major contribution to the high fidelity of calf thymus DNA polymerase-α1989 · 129 citations
  5. 5Structural Studies of DNA Fragments: The G·T Wobble Base Pair in A, B and Z DNA; The G·A Base Pair in B-DNA1985 · 134 citations